Excess ethanol depletes catecholamines, taxes adrenal output, and generates reactive aldehydes that inflame the brain. Rapid nutrient replacement limits next-day fatigue and neuroinflammation. Tyrosine, taurine, and a full methyl-B complex replenish dopamine precursors and one-carbon cofactors, accelerating detoxification of acetaldehyde. Adaptogenic ashwagandha and cordyceps temper cortisol spikes while soothing fiber eases gastric irritation, helping patients rebound in both mood and gut comfort.